Human CD26 is a T cell activation antigen which can be associated with costimulation (1). The significance of the dipeptidyl peptidase IV activity remains unknown. Characterization of adenosine deaminase binding to CD26 suggests an important immunoregulatory role (2). Soluble CD26 serum levels are predictive for colorectal cancer (3). CD26 is expressed at high levels on CD4+ Th17 T cells (4).
Isotype: Murine IgG2b
Immunogen: Human T cell clone
Specificity: Antibody 202.36 reacts with the type II membrane protein CD26.
References:
1.) Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford (1995) p. 1105-1114.
2.) R.P. Dong, et al, (1996) J Immunol 156: 1349-1355.
3.) OJ Cordero, M Páez de la Cadena, et al, (2000) British Journal of Cancer 83(9), 1139–1146.
4.) Bengsch B, R Thimme, et al, (2012) J Immunol 188(11): 5438-5447.
Ancell世界著名的专注做人种属的流试抗体提供商。提供FITC、PE、APC、生物素和纯化human 抗体,可用于流式,FA 实验。并提供融合蛋白。