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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Ancell/anti-CD70/120 tests/222-050
产品编号:222-050
市  场 价:¥5000.00
场      地:美国(厂家直采)
产品分类: 细胞相关>细胞株>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$250.00
品      牌: Ancell
公      司:Ancell
公司分类:
Ancell/anti-CD70/120 tests/222-050
商品介绍

Human CD70 is not present on resting lymphocytes. CD70 is expressed after activation on about 20% of T cells and on about 70% of B cells. CD70 is a ligand for CD27 and it is also a member of the tumor necrosis factor gene family (3).

Isotype: Murine IgG1

Immunogen: Human WM-1 (Waldenström’s macroglobulinemia) cell line

Specificity: Antibody BU69 recognizes the CD70 molecule of approximately 30 kd (3).

Functional Application: Antibody BU69 blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells(5).

References:

1. R.Q. Hintzen, et al, (1994) J Immunol 152: 1762-1773.

2. M.R. Bowman, et al, (1994) J Immunol 152: 1756-1761.

3. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1137-1138.

4. K. Agematsu, et al, (1995) J Immunol 154: 3627-3635.

5. S Iwamoto, A Miyazaki, et al, (2005) J Leuk Biol 78: 383-392.

6. Wischhusen J, M Weller, et al. (2002) Cancer Res 62: 2592-2599

7. P.J. Adams, A.L. Harris, et al.(2006) British J Cancer 95:298-306.

8. C Muller, R Kuppers, et al.(2010) Intl Immunol 22(4):289-298.

9. H Yokoi, H Yoshikawa, et al (2003) Lymphology 36: 3674-83. PMID: 12926832

品牌介绍

Ancell世界著名的专注做人种属的流试抗体提供商。提供FITC、PE、APC、生物素和纯化human 抗体,可用于流式,FA 实验。并提供融合蛋白。

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