Human CD48 (SLAMF2) is a GPI anchored cell surface gylcoprotein found on all lymphocytes and monocytes. CD48 is a ligand for CD2 as well as CD229 and CD244(2B4, SLAMF4), and may be involved in enhancing the activating signal to B cells.

Isotype: Murine IgG2a

Immunogen: Human PBLs

Specificity: Clone 5-4.8 recognizes epitope 4 of the CD48 molecule of about 47 kd (4). This mAb blocks binding of biotinylated recombinant CD244(2B4,SLAMF4)-muIg (Cat# 544-030) to CD48 in FACS.

References:

1. H.A. Vaughan, et al, (1983) Transplantation 36: 446-450.

2. H.A. Vaughan, et al, (1991) Immunogenetics 33: 113-117.

3. E.N. Klyushnenkova, et al, (1996) Cellular Immunol 174: 90-98.

4. Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 509-512.

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