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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Ancell/anti-CD40/100 g/300-030
产品编号:300-030
市  场 价:¥3700.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$185.00
品      牌: Ancell
公      司:Ancell
公司分类:
Ancell/anti-CD40/100 g/300-030
商品介绍

Human CD40 is a member of the tumor necrosis factor (TNF) receptor family and is present on all B cells except plasma cells. CD40 is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. CD40 plays an important role in B cell activation and the interaction with its ligand CD154 (CD40 Ligand) is essential for isotype switching (5).

Isotype: Murine IgG1

Immunogen: Murine L cells transfectants expressing human CD40

Specificity: Antibody EA-5 recognizes the CD40 molecule of about 44 kd (1, 2, 3).

Functional Application: Binding of cross linked EA-5 will partially activate B cells.

References:

1. C.L. Law, B. Wormann & T.W. LeBien, (1990) Leukemia 4: 732-738.

2. A.W. Larson & T.W. LeBien, (1994) J Immunol 153: 584-594.

3. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 547-556.

4. E. Lindout, et al, (1995) J Exp med 181:1985-1995.

5. T.M. Foy, R.J Noelle et al, (1996) Annu Rev Immunol 14:591-617.

品牌介绍

Ancell世界著名的专注做人种属的流试抗体提供商。提供FITC、PE、APC、生物素和纯化human 抗体,可用于流式,FA 实验。并提供融合蛋白。

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